Same bridge, new destinations rethinking paradigms for mechanical cardiac support in heart failure.


Journal Article

Mechanical cardiac support with ventricular assist devices is an established therapy for a variety of clinical scenarios, including postcardiotomy shock, "bridge to transplant," and "destination therapy." At present, device development, clinical trial design, regulatory approval, and reimbursement decisions for the clinical application of mechanical cardiac support devices continue to be considered in the context of these clinical indications. Although understandable from a historical perspective, these arbitrary divisions are inconsistent with the clinical realities of advanced heart failure therapy. By narrowly focusing on transplant eligibility at a static point in the clinical course, current guidelines impede the broader application of ventricular assist device technology to the growing population of patients who may benefit from this therapy.

Full Text

Duke Authors

Cited Authors

  • Felker, GM; Rogers, JG

Published Date

  • March 7, 2006

Published In

Volume / Issue

  • 47 / 5

Start / End Page

  • 930 - 932

PubMed ID

  • 16516073

Pubmed Central ID

  • 16516073

Electronic International Standard Serial Number (EISSN)

  • 1558-3597

Digital Object Identifier (DOI)

  • 10.1016/j.jacc.2005.09.070


  • eng

Conference Location

  • United States