The genetics of primary open-angle glaucoma: a review.
Publication
, Journal Article
Allingham, RR; Liu, Y; Rhee, DJ
Published in: Exp Eye Res
April 2009
Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder and affects more than 2 million individuals in the United States. It has become increasingly clear that a host of genetic as well as environmental factors are likely to contribute to the phenotype. A number of chromosomal and genetic associations have been reported for POAG. This review examines what is currently known about the underlying genetic structure, what remains to be learned, and how this may affect our medical management of this major blinding disease.
Duke Scholars
Published In
Exp Eye Res
DOI
EISSN
1096-0007
Publication Date
April 2009
Volume
88
Issue
4
Start / End Page
837 / 844
Location
England
Related Subject Headings
- Transcription Factor TFIIIA
- Ophthalmology & Optometry
- Mutation
- Membrane Transport Proteins
- Humans
- Glycoproteins
- Glaucoma, Open-Angle
- Genetic Predisposition to Disease
- Genetic Linkage
- Eye Proteins
Citation
APA
Chicago
ICMJE
MLA
NLM
Allingham, R. R., Liu, Y., & Rhee, D. J. (2009). The genetics of primary open-angle glaucoma: a review. Exp Eye Res, 88(4), 837–844. https://doi.org/10.1016/j.exer.2008.11.003
Allingham, R Rand, Yutao Liu, and Douglas J. Rhee. “The genetics of primary open-angle glaucoma: a review.” Exp Eye Res 88, no. 4 (April 2009): 837–44. https://doi.org/10.1016/j.exer.2008.11.003.
Allingham RR, Liu Y, Rhee DJ. The genetics of primary open-angle glaucoma: a review. Exp Eye Res. 2009 Apr;88(4):837–44.
Allingham, R. Rand, et al. “The genetics of primary open-angle glaucoma: a review.” Exp Eye Res, vol. 88, no. 4, Apr. 2009, pp. 837–44. Pubmed, doi:10.1016/j.exer.2008.11.003.
Allingham RR, Liu Y, Rhee DJ. The genetics of primary open-angle glaucoma: a review. Exp Eye Res. 2009 Apr;88(4):837–844.
Published In
Exp Eye Res
DOI
EISSN
1096-0007
Publication Date
April 2009
Volume
88
Issue
4
Start / End Page
837 / 844
Location
England
Related Subject Headings
- Transcription Factor TFIIIA
- Ophthalmology & Optometry
- Mutation
- Membrane Transport Proteins
- Humans
- Glycoproteins
- Glaucoma, Open-Angle
- Genetic Predisposition to Disease
- Genetic Linkage
- Eye Proteins