The genetics of primary open-angle glaucoma: a review.

Journal Article (Journal Article;Review)

Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder and affects more than 2 million individuals in the United States. It has become increasingly clear that a host of genetic as well as environmental factors are likely to contribute to the phenotype. A number of chromosomal and genetic associations have been reported for POAG. This review examines what is currently known about the underlying genetic structure, what remains to be learned, and how this may affect our medical management of this major blinding disease.

Full Text

Duke Authors

Cited Authors

  • Allingham, RR; Liu, Y; Rhee, DJ

Published Date

  • April 2009

Published In

Volume / Issue

  • 88 / 4

Start / End Page

  • 837 - 844

PubMed ID

  • 19061886

Pubmed Central ID

  • PMC7006834

Electronic International Standard Serial Number (EISSN)

  • 1096-0007

Digital Object Identifier (DOI)

  • 10.1016/j.exer.2008.11.003


  • eng

Conference Location

  • England