Beyond 5-fluorouracil: the emerging role of newer chemotherapeutics and targeted agents with radiation therapy.

Journal Article (Review)

The management of rectal cancer has undergone significant evolution with advances in surgery, radiation therapy, and chemotherapy. These advances have translated into improved rates of local control, survival, and quality of life. More recently, the integration of newer chemotherapeutic and targeted agents in patients with advanced colorectal cancer have led to further improvements in disease-free and overall survival. These agents are now being studied with radiation therapy in the neoadjuvant therapy of rectal cancer.

Full Text

Duke Authors

Cited Authors

  • Czito, BG; Willett, CG

Published Date

  • July 2011

Published In

Volume / Issue

  • 21 / 3

Start / End Page

  • 203 - 211

PubMed ID

  • 21645865

Pubmed Central ID

  • 21645865

Electronic International Standard Serial Number (EISSN)

  • 1532-9461

Digital Object Identifier (DOI)

  • 10.1016/j.semradonc.2011.02.006


  • eng

Conference Location

  • United States