Update on treatment advances in combined-modality therapy for anal and rectal carcinomas.

Journal Article (Journal Article;Review)

Concurrent radiation therapy and chemotherapy is the primary treatment for patients with squamous cell tumors of the anal canal, and is also employed in the neoadjuvant setting for patients with stage II and III adenocarcinoma of the rectum. There is constant clinical study involving modifications of chemoradiotherapy regimens in an effort to maximize tumor responses while reducing normal tissue toxicity. This review will discuss established regimens as well as newer and novel treatment approaches to treatment of anal and rectal cancer.

Full Text

Duke Authors

Cited Authors

  • Meyer, J; Balch, G; Willett, C; Czito, B

Published Date

  • June 2011

Published In

Volume / Issue

  • 13 / 3

Start / End Page

  • 177 - 185

PubMed ID

  • 21465120

Electronic International Standard Serial Number (EISSN)

  • 1534-6269

Digital Object Identifier (DOI)

  • 10.1007/s11912-011-0166-z


  • eng

Conference Location

  • United States