Successful extracorporeal membrane oxygenation for respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation.

Journal Article

We report the first successful use of venovenous extracorporeal membrane oxygenation (ECMO) for refractory respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation. A 23-month-old female with complete immune-incompetent DiGeorge anomaly 65 days after allogenic thymus transplantation was treated in our pediatric intensive care unit for acute respiratory failure secondary to bacterial sepsis. She subsequently developed acute hypercarbic respiratory failure unresponsive to conventional medical therapy. She was successfully managed with venovenous ECMO for 4 days, with complete resolution of her respiratory symptoms. This case demonstrates the complex decision making process regarding initiation of ECMO in patients with severe immunodeficiency.

Full Text

Duke Authors

Cited Authors

  • Hornik, CP; Hartman, ME; Markert, ML; Lodge, AJ; Cheifetz, IM; Turner, DA

Published Date

  • June 2011

Published In

Volume / Issue

  • 56 / 6

Start / End Page

  • 866 - 870

PubMed ID

  • 21333090

International Standard Serial Number (ISSN)

  • 0020-1324

Digital Object Identifier (DOI)

  • 10.4187/respcare.01051

Language

  • eng

Conference Location

  • United States