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Orbital involvement by Wegener's granulomatosis: imaging findings.

Publication ,  Journal Article
Provenzale, JM; Mukherji, S; Allen, NB; Castillo, M; Weber, AW
Published in: AJR Am J Roentgenol
April 1996

OBJECTIVE: The purpose of this study was to define patterns of Wegener's granulomatosis (WG) orbital disease involvement. SUBJECTS AND METHODS: We evaluated the orbital examinations of 14 WG patients (CT for nine, MR imaging for three, and both CT and MR imaging for two) for the number of involved orbits, intraconal or extraconal location, involvement of the orbital apex, sinus involvement, bony erosion, and optic nerve compression. MR images were analyzed for signal characteristics and enhancement patterns. RESULTS: We found orbital disease to be unilateral in 12 patients (86%) and bilateral in two patients (14%) (total of 16 orbits). In 11 orbits (69%), coexistent orbital and sinus diseases with bony erosion were present. Orbital disease without sinus disease was seen in five orbits (31%). Intraorbital disease distribution was as follows: solely extraconal--seven orbits (44%) (four with involvement of muscle); intraconal with muscular involvement--one orbit (6%); combined intra- and extraconal--seven orbits (44%); and primarily orbital apex--one orbit (6%). Involvement of the apex was seen in six orbits. The WG mass was hypointense relative to orbital fat on three standard T2-weighted MR images. We saw homogeneous MR contrast enhancement in all four orbits studied on enhanced T1-weighted images. CONCLUSION: Intraorbital WG involvement is usually accompanied by paranasal sinus disease. A hypointense signal on T2-weighted MR images is helpful in suggesting the diagnosis.

Duke Scholars

Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

April 1996

Volume

166

Issue

4

Start / End Page

929 / 934

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Orbital Diseases
  • Orbit
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Granulomatosis with Polyangiitis
 

Citation

APA
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ICMJE
MLA
NLM
Provenzale, J. M., Mukherji, S., Allen, N. B., Castillo, M., & Weber, A. W. (1996). Orbital involvement by Wegener's granulomatosis: imaging findings. AJR Am J Roentgenol, 166(4), 929–934. https://doi.org/10.2214/ajr.166.4.8610576
Provenzale, J. M., S. Mukherji, N. B. Allen, M. Castillo, and A. W. Weber. “Orbital involvement by Wegener's granulomatosis: imaging findings.AJR Am J Roentgenol 166, no. 4 (April 1996): 929–34. https://doi.org/10.2214/ajr.166.4.8610576.
Provenzale JM, Mukherji S, Allen NB, Castillo M, Weber AW. Orbital involvement by Wegener's granulomatosis: imaging findings. AJR Am J Roentgenol. 1996 Apr;166(4):929–34.
Provenzale, J. M., et al. “Orbital involvement by Wegener's granulomatosis: imaging findings.AJR Am J Roentgenol, vol. 166, no. 4, Apr. 1996, pp. 929–34. Pubmed, doi:10.2214/ajr.166.4.8610576.
Provenzale JM, Mukherji S, Allen NB, Castillo M, Weber AW. Orbital involvement by Wegener's granulomatosis: imaging findings. AJR Am J Roentgenol. 1996 Apr;166(4):929–934.

Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

April 1996

Volume

166

Issue

4

Start / End Page

929 / 934

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Orbital Diseases
  • Orbit
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Granulomatosis with Polyangiitis