MRI lesion severity and mortality in geriatric depression.
OBJECTIVE: The authors correlated magnetic resonance imaging (MRI) lesion severity and mortality among depressed elderly patients. METHOD: They examined the association of mortality and deep white-matter hyperintensity (DWMH), periventricular hyperintensity (PVH), and subcortical gray-matter hyperintensity (SGH) ratings in 259 subjects. RESULTS: DWMH and PVH were significantly associated with mortality initially, and, in final modeling, DWMH remained significant. CONCLUSION: These findings suggest that there is a relationship between cerebrovascular disease severity and mortality among depressed patients. More studies, with larger sample sizes, comparing depressed patients and control subjects are needed to further elucidate this relationship.
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Related Subject Headings
- Male
- Magnetic Resonance Imaging
- Humans
- Geriatrics
- Follow-Up Studies
- Female
- Depression
- Cerebrovascular Disorders
- Brain
- Aged
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Male
- Magnetic Resonance Imaging
- Humans
- Geriatrics
- Follow-Up Studies
- Female
- Depression
- Cerebrovascular Disorders
- Brain
- Aged