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MRI lesion severity and mortality in geriatric depression.

Publication ,  Journal Article
Levy, RM; Steffens, DC; McQuoid, DR; Provenzale, JM; MacFall, JR; Krishnan, KRR
Published in: Am J Geriatr Psychiatry
2003

OBJECTIVE: The authors correlated magnetic resonance imaging (MRI) lesion severity and mortality among depressed elderly patients. METHOD: They examined the association of mortality and deep white-matter hyperintensity (DWMH), periventricular hyperintensity (PVH), and subcortical gray-matter hyperintensity (SGH) ratings in 259 subjects. RESULTS: DWMH and PVH were significantly associated with mortality initially, and, in final modeling, DWMH remained significant. CONCLUSION: These findings suggest that there is a relationship between cerebrovascular disease severity and mortality among depressed patients. More studies, with larger sample sizes, comparing depressed patients and control subjects are needed to further elucidate this relationship.

Duke Scholars

Published In

Am J Geriatr Psychiatry

DOI

ISSN

1064-7481

Publication Date

2003

Volume

11

Issue

6

Start / End Page

678 / 682

Location

England

Related Subject Headings

  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Geriatrics
  • Follow-Up Studies
  • Female
  • Depression
  • Cerebrovascular Disorders
  • Brain
  • Aged
 

Citation

APA
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ICMJE
MLA
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Levy, R. M., Steffens, D. C., McQuoid, D. R., Provenzale, J. M., MacFall, J. R., & Krishnan, K. R. R. (2003). MRI lesion severity and mortality in geriatric depression. Am J Geriatr Psychiatry, 11(6), 678–682. https://doi.org/10.1176/appi.ajgp.11.6.678
Levy, Robert M., David C. Steffens, Douglas R. McQuoid, James M. Provenzale, James R. MacFall, and K Ranga Rama Krishnan. “MRI lesion severity and mortality in geriatric depression.Am J Geriatr Psychiatry 11, no. 6 (2003): 678–82. https://doi.org/10.1176/appi.ajgp.11.6.678.
Levy RM, Steffens DC, McQuoid DR, Provenzale JM, MacFall JR, Krishnan KRR. MRI lesion severity and mortality in geriatric depression. Am J Geriatr Psychiatry. 2003;11(6):678–82.
Levy, Robert M., et al. “MRI lesion severity and mortality in geriatric depression.Am J Geriatr Psychiatry, vol. 11, no. 6, 2003, pp. 678–82. Pubmed, doi:10.1176/appi.ajgp.11.6.678.
Levy RM, Steffens DC, McQuoid DR, Provenzale JM, MacFall JR, Krishnan KRR. MRI lesion severity and mortality in geriatric depression. Am J Geriatr Psychiatry. 2003;11(6):678–682.
Journal cover image

Published In

Am J Geriatr Psychiatry

DOI

ISSN

1064-7481

Publication Date

2003

Volume

11

Issue

6

Start / End Page

678 / 682

Location

England

Related Subject Headings

  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Geriatrics
  • Follow-Up Studies
  • Female
  • Depression
  • Cerebrovascular Disorders
  • Brain
  • Aged