Is there a best way to set positive expiratory-end pressure for mechanical ventilatory support in acute lung injury?
Journal Article (Review)
Airspace collapse is a hallmark of parenchymal lung injury. Strategies to reopen and maintain patency of these regions offer three advantages: improved gas exchange, less lung injury, and improved lung compliance. Elevations in intrathoracic pressure to achieve these goals, however, may overdistend healthier lung regions and compromise cardiac function. Positive expiratory-end pressure is a widely used technique to maintain alveolar patency, but its beneficial effects must be balanced against its harmful effects.
Full Text
Duke Authors
Cited Authors
- MacIntyre, NR
Published Date
- June 2008
Published In
Volume / Issue
- 29 / 2
Start / End Page
- 233 - v
PubMed ID
- 18440433
Pubmed Central ID
- 18440433
International Standard Serial Number (ISSN)
- 0272-5231
Digital Object Identifier (DOI)
- 10.1016/j.ccm.2008.01.005
Language
- eng
Conference Location
- United States