Chronic obstructive pulmonary disease: emerging medical therapies.
Publication
, Journal Article
MacIntyre, NR
Published in: Respir Care
January 2004
As many as 10 million Americans have chronic obstructive pulmonary disease and as a consequence experience disabling symptoms, high cost of care, and substantial mortality. Several new approaches are being investigated for possible benefit in managing (or even reversing) chronic obstructive pulmonary disease. This article reviews 4 new approaches that are either in or close to phase III trials: long-acting bronchodilators, phosphodiesterase-4 inhibitors, vasodilators, and retinoids. Of those tiotropium appears to be the closest to receiving clinical approval in the United States. The risk/benefit ratio and the cost-effectiveness of the other compounds are less clear and await additional study.
Duke Scholars
Published In
Respir Care
ISSN
0020-1324
Publication Date
January 2004
Volume
49
Issue
1
Start / End Page
64 / 69
Location
United States
Related Subject Headings
- Vasodilator Agents
- Respiratory System
- Quality of Life
- Pulmonary Emphysema
- Pulmonary Disease, Chronic Obstructive
- Pulmonary Alveoli
- Phosphodiesterase Inhibitors
- Humans
- Bronchodilator Agents
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
MacIntyre, N. R. (2004). Chronic obstructive pulmonary disease: emerging medical therapies. Respir Care, 49(1), 64–69.
MacIntyre, Neil R. “Chronic obstructive pulmonary disease: emerging medical therapies.” Respir Care 49, no. 1 (January 2004): 64–69.
MacIntyre NR. Chronic obstructive pulmonary disease: emerging medical therapies. Respir Care. 2004 Jan;49(1):64–9.
MacIntyre, Neil R. “Chronic obstructive pulmonary disease: emerging medical therapies.” Respir Care, vol. 49, no. 1, Jan. 2004, pp. 64–69.
MacIntyre NR. Chronic obstructive pulmonary disease: emerging medical therapies. Respir Care. 2004 Jan;49(1):64–69.
Published In
Respir Care
ISSN
0020-1324
Publication Date
January 2004
Volume
49
Issue
1
Start / End Page
64 / 69
Location
United States
Related Subject Headings
- Vasodilator Agents
- Respiratory System
- Quality of Life
- Pulmonary Emphysema
- Pulmonary Disease, Chronic Obstructive
- Pulmonary Alveoli
- Phosphodiesterase Inhibitors
- Humans
- Bronchodilator Agents
- Animals