Are there benefits or harm from pressure targeting during lung-protective ventilation?

Journal Article (Journal Article)

Mechanically, breath design is usually either flow/volume-targeted or pressure-targeted. Both approaches can effectively provide lung-protective ventilation, but they prioritize different ventilation parameters, so their responses to changing respiratory-system mechanics and patient effort are different. These different response behaviors have advantages and disadvantages that can be important in specific circumstances. Flow/volume targeting guarantees a set minute ventilation but sometimes may be difficult to synchronize with patient effort, and it will not limit inspiratory pressure. In contrast, pressure targeting, with its variable flow, may be easier to synchronize and will limit inspiratory pressure, but it provides no control over delivered volume. Skilled clinicians can maximize benefits and minimize problems with either flow/volume targeting or pressure targeting. Indeed, as is often the case in managing complex life-support devices, it is operator expertise rather than the device design features that most impacts patient outcomes.

Full Text

Duke Authors

Cited Authors

  • MacIntyre, NR; Sessler, CN

Published Date

  • February 2010

Published In

Volume / Issue

  • 55 / 2

Start / End Page

  • 175 - 180

PubMed ID

  • 20105343

International Standard Serial Number (ISSN)

  • 0020-1324


  • eng

Conference Location

  • United States