Risk factors and prevention of late-onset sepsis in premature infants.

Journal Article (Journal Article;Review)

Late-onset sepsis in premature infants is a major cause of morbidity, mortality, and increased medical costs. Risk factors include low birth weight, low gestational age, previous antimicrobial exposure, poor hand hygiene, and central venous catheters. Methods studied to prevent late-onset sepsis include early feedings, immune globulin administration, prophylactic antimicrobial administration, and improved hand hygiene. In this review, we will outline the risk factors for development of late-onset sepsis and evidence supporting methods for prevention of late-onset sepsis in premature infants.

Full Text

Duke Authors

Cited Authors

  • Downey, LC; Smith, PB; Benjamin, DK

Published Date

  • July 2010

Published In

Volume / Issue

  • 86 Suppl 1 / Suppl 1

Start / End Page

  • 7 - 12

PubMed ID

  • 20116186

Pubmed Central ID

  • PMC2889164

Electronic International Standard Serial Number (EISSN)

  • 1872-6232

Digital Object Identifier (DOI)

  • 10.1016/j.earlhumdev.2010.01.012


  • eng

Conference Location

  • Ireland