Ultrafast 1D MR thermometry using phase or frequency mapping.
OBJECT: To develop an ultrafast MRI-based temperature monitoring method for application during rapid ultrasound exposures in moving organs. MATERIALS AND METHODS: A slice selective 90° - 180° pair of RF pulses was used to solicit an echo from a column, which was then sampled with a train of gradient echoes. In a gel phantom, phase changes of each echo were compared to standard gradient-echo thermometry, and temperature monitoring was tested during focused ultrasound sonications. Signal-to-noise ratio (SNR) performance was evaluated in vivo in a rabbit brain, and feasibility was tested in a human heart. RESULTS: The correlation between each echo in the acquisition and MRI-based temperature measurements was good (R = 0.98 ± 0.03). A temperature sampling rate of 19 Hz was achieved at 3T in the gel phantom. It was possible to acquire the water frequency in the beating heart muscle with 5-Hz sampling rate during a breath hold. CONCLUSION: Ultrafast thermometry via phase or frequency monitoring along single columns was demonstrated. With a temporal resolution around 50 ms, it may be possible to monitor focal heating produced by short ultrasound pulses.
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Related Subject Headings
- Water
- Ultrasonics
- Temperature
- Signal-To-Noise Ratio
- Radio Waves
- Rabbits
- Protons
- Phantoms, Imaging
- Nuclear Medicine & Medical Imaging
- Myocardium
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Water
- Ultrasonics
- Temperature
- Signal-To-Noise Ratio
- Radio Waves
- Rabbits
- Protons
- Phantoms, Imaging
- Nuclear Medicine & Medical Imaging
- Myocardium