Safety evaluation of fospropofol for sedation during minor surgical procedures.

Published

Journal Article

STUDY OBJECTIVE: To evaluate the safety of intravenous (IV) fospropofol when used to provide minimal to moderate sedation in patients undergoing minor surgical procedures. DESIGN: Phase 3, open-label, single-arm study. SETTING: Multi-center. PATIENTS: 123 ASA physical status I, II, III, and IV patients, aged>or=18 years. INTERVENTIONS: Patients were pretreated with fentanyl 50 microg before receiving an initial dose of IV fospropofol 6.5 mg/kg. Patients could receive up to 5 supplemental doses of fospropofol 1.63 mg/kg to reach a Modified Observer's Assessment of Alertness/Sedation (MOAA/S) score

Full Text

Cited Authors

  • Gan, TJ; Berry, BD; Ekman, EF; Muckerman, RC; Shore, N; Hardi, R

Published Date

  • June 2010

Published In

Volume / Issue

  • 22 / 4

Start / End Page

  • 260 - 267

PubMed ID

  • 20522356

Pubmed Central ID

  • 20522356

Electronic International Standard Serial Number (EISSN)

  • 1873-4529

International Standard Serial Number (ISSN)

  • 0952-8180

Digital Object Identifier (DOI)

  • 10.1016/j.jclinane.2009.08.007

Language

  • eng