Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5.
Journal Article (Journal Article)
Using a monoclonal antibody (A2B5), which binds to GQ ganglioside, and tetanus toxin, which binds to GD and GT gangliosides, distinct regions of human and rodent thymic epithelial cells have been identified. The lymphoid elements of the thymus do not bind A2B5 or tetanus toxin. The A2B5 and tetanus toxin-binding cells form a network of thymic epithelial cells throughout the thymic subcapsular cortex and thymic medulla and contain thymopoietin and thymosin alpha-1.
Full Text
Duke Authors
Cited Authors
- Haynes, BF; Shimizu, K; Eisenbarth, GS
Published Date
- January 1983
Published In
Volume / Issue
- 71 / 1
Start / End Page
- 9 - 14
PubMed ID
- 6336763
Pubmed Central ID
- PMC436832
International Standard Serial Number (ISSN)
- 0021-9738
Digital Object Identifier (DOI)
- 10.1172/jci110755
Language
- eng
Conference Location
- United States