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Hemolytic transfusion reactions caused by failure of commercial antiglobulin reagents to detect complement.

Publication ,  Journal Article
Sherwood, GK; Haynes, BF; Rosse, WF
Published in: Transfusion
1976

Two definite acute hemolytic transfusion reactions occurred in a patient with chronic myelogenous leukemia in blastic crisis. Both suspect units were entirely compatible by routine crossmatch using commercial antiblobulin sera. However, both units were clearly incompatible using our own specific anti-C3 antiserum in the antiglobulin reaction phase of the crossmatch. Subsequently it was possible to predict in vivo compatibility using our anti-C3 antiserum in vitro. This case adds new evidence for the inadequacy of anticomplement activity in commercial antisera.

Duke Scholars

Published In

Transfusion

DOI

ISSN

0041-1132

Publication Date

1976

Volume

16

Issue

5

Start / End Page

417 / 420

Location

United States

Related Subject Headings

  • Transfusion Reaction
  • Male
  • Lutheran Blood-Group System
  • Leukemia, Myeloid
  • Isoantibodies
  • Immune Sera
  • Humans
  • Hemolysis
  • Coombs Test
  • Complement System Proteins
 

Citation

APA
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ICMJE
MLA
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Sherwood, G. K., Haynes, B. F., & Rosse, W. F. (1976). Hemolytic transfusion reactions caused by failure of commercial antiglobulin reagents to detect complement. Transfusion, 16(5), 417–420. https://doi.org/10.1046/j.1537-2995.1976.16577039295.x
Sherwood, G. K., B. F. Haynes, and W. F. Rosse. “Hemolytic transfusion reactions caused by failure of commercial antiglobulin reagents to detect complement.Transfusion 16, no. 5 (1976): 417–20. https://doi.org/10.1046/j.1537-2995.1976.16577039295.x.
Sherwood, G. K., et al. “Hemolytic transfusion reactions caused by failure of commercial antiglobulin reagents to detect complement.Transfusion, vol. 16, no. 5, 1976, pp. 417–20. Pubmed, doi:10.1046/j.1537-2995.1976.16577039295.x.
Journal cover image

Published In

Transfusion

DOI

ISSN

0041-1132

Publication Date

1976

Volume

16

Issue

5

Start / End Page

417 / 420

Location

United States

Related Subject Headings

  • Transfusion Reaction
  • Male
  • Lutheran Blood-Group System
  • Leukemia, Myeloid
  • Isoantibodies
  • Immune Sera
  • Humans
  • Hemolysis
  • Coombs Test
  • Complement System Proteins