Monoclonal antibodies to a human islet cell surface glycoprotein: 4F2 and LC7-2.
Publication
, Journal Article
Srikanta, S; Telen, M; Posillico, JT; Dolinar, R; Krisch, K; Haynes, BF; Eisenbarth, GS
Published in: Endocrinology
June 1987
Monoclonal antibodies 4F2 and LC7-2 react with a cell surface differentiation antigen expressed by the endocrine cells of the human pancreatic islet, but not by the acinar pancreatic, ductular, vascular, or stromal connective tissue cells. Western immunoblotting procedures demonstrate the reactivity of the monoclonal antibody 4F2 with a 120 kilodalton islet cell protein in detergent-solubilized cell extracts. These two monoclonal antibodies have potential for application in many aspects of islet cell research and diabetes in general.
Duke Scholars
Published In
Endocrinology
DOI
ISSN
0013-7227
Publication Date
June 1987
Volume
120
Issue
6
Start / End Page
2240 / 2244
Location
United States
Related Subject Headings
- Molecular Weight
- Islets of Langerhans
- Immunologic Techniques
- Humans
- Glycoproteins
- Epitopes
- Endocrinology & Metabolism
- Cell Separation
- Cell Differentiation
- Antigens, Surface
Citation
APA
Chicago
ICMJE
MLA
NLM
Srikanta, S., Telen, M., Posillico, J. T., Dolinar, R., Krisch, K., Haynes, B. F., & Eisenbarth, G. S. (1987). Monoclonal antibodies to a human islet cell surface glycoprotein: 4F2 and LC7-2. Endocrinology, 120(6), 2240–2244. https://doi.org/10.1210/endo-120-6-2240
Srikanta, S., M. Telen, J. T. Posillico, R. Dolinar, K. Krisch, B. F. Haynes, and G. S. Eisenbarth. “Monoclonal antibodies to a human islet cell surface glycoprotein: 4F2 and LC7-2.” Endocrinology 120, no. 6 (June 1987): 2240–44. https://doi.org/10.1210/endo-120-6-2240.
Srikanta S, Telen M, Posillico JT, Dolinar R, Krisch K, Haynes BF, et al. Monoclonal antibodies to a human islet cell surface glycoprotein: 4F2 and LC7-2. Endocrinology. 1987 Jun;120(6):2240–4.
Srikanta, S., et al. “Monoclonal antibodies to a human islet cell surface glycoprotein: 4F2 and LC7-2.” Endocrinology, vol. 120, no. 6, June 1987, pp. 2240–44. Pubmed, doi:10.1210/endo-120-6-2240.
Srikanta S, Telen M, Posillico JT, Dolinar R, Krisch K, Haynes BF, Eisenbarth GS. Monoclonal antibodies to a human islet cell surface glycoprotein: 4F2 and LC7-2. Endocrinology. 1987 Jun;120(6):2240–2244.
Published In
Endocrinology
DOI
ISSN
0013-7227
Publication Date
June 1987
Volume
120
Issue
6
Start / End Page
2240 / 2244
Location
United States
Related Subject Headings
- Molecular Weight
- Islets of Langerhans
- Immunologic Techniques
- Humans
- Glycoproteins
- Epitopes
- Endocrinology & Metabolism
- Cell Separation
- Cell Differentiation
- Antigens, Surface