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Toward an understanding of the correlates of protective immunity to HIV infection.

Publication ,  Journal Article
Haynes, BF; Pantaleo, G; Fauci, AS
Published in: Science
January 19, 1996

Considerable progress has been made recently in understanding the genetic, immunologic and virologic factors in human immunodeficiency virus (HIV)-infected individuals who either rapidly progress or do not progress to acquired immunodeficiency syndrome (AIDS). In addition, detection of HIV-specific immune responses in HIV-negative individuals who have been exposed to the virus multiple times suggests that natural immune responses to HIV may be protective in rare individuals. Understanding the correlates of protective immunity to HIV infection is critical to efforts to develop preventive HIV vaccines as well as to determine the feasibility of treating HIV infection by boosting immunity to HIV.

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Published In

Science

DOI

ISSN

0036-8075

Publication Date

January 19, 1996

Volume

271

Issue

5247

Start / End Page

324 / 328

Location

United States

Related Subject Headings

  • Virus Replication
  • T-Lymphocytes
  • Major Histocompatibility Complex
  • Humans
  • HIV Seronegativity
  • HIV Infections
  • HIV Antibodies
  • HIV
  • General Science & Technology
  • Disease Progression
 

Citation

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Haynes, B. F., Pantaleo, G., & Fauci, A. S. (1996). Toward an understanding of the correlates of protective immunity to HIV infection. Science, 271(5247), 324–328. https://doi.org/10.1126/science.271.5247.324
Haynes, B. F., G. Pantaleo, and A. S. Fauci. “Toward an understanding of the correlates of protective immunity to HIV infection.Science 271, no. 5247 (January 19, 1996): 324–28. https://doi.org/10.1126/science.271.5247.324.
Haynes BF, Pantaleo G, Fauci AS. Toward an understanding of the correlates of protective immunity to HIV infection. Science. 1996 Jan 19;271(5247):324–8.
Haynes, B. F., et al. “Toward an understanding of the correlates of protective immunity to HIV infection.Science, vol. 271, no. 5247, Jan. 1996, pp. 324–28. Pubmed, doi:10.1126/science.271.5247.324.
Haynes BF, Pantaleo G, Fauci AS. Toward an understanding of the correlates of protective immunity to HIV infection. Science. 1996 Jan 19;271(5247):324–328.
Journal cover image

Published In

Science

DOI

ISSN

0036-8075

Publication Date

January 19, 1996

Volume

271

Issue

5247

Start / End Page

324 / 328

Location

United States

Related Subject Headings

  • Virus Replication
  • T-Lymphocytes
  • Major Histocompatibility Complex
  • Humans
  • HIV Seronegativity
  • HIV Infections
  • HIV Antibodies
  • HIV
  • General Science & Technology
  • Disease Progression