Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.
Publication
, Journal Article
Levine, MN; Fay, JW; Jones, NH; Metzgar, RS; Haynes, BF
Published in: Blood
November 1981
Cell surface antigens of the human bone marrow CFU-C have been studied. Human marrow cells were incubated with a variety of monoclonal antisera and complement prior to culture in semisolid media. By using indirect immunofluorescent studies, the percentage of bone marrow cells binding the antibodies was determined. The CFU-C phenotype is HLA+, la+, 4F2+, 3A1-, and DUALL-1-. This study provides information that is useful in the study of myeloid cell ontogeny and necessary for the use of some of these reagents in the treatment of bone marrow cells prior to human bone marrow transplantation in various clinical settings.
Duke Scholars
Published In
Blood
ISSN
0006-4971
Publication Date
November 1981
Volume
58
Issue
5
Start / End Page
1047 / 1049
Location
United States
Related Subject Headings
- Rabbits
- Phenotype
- Macrophages
- Immunology
- Immune Sera
- Humans
- Histocompatibility Antigens Class II
- HLA Antigens
- Granulocytes
- Cytotoxicity, Immunologic
Citation
APA
Chicago
ICMJE
MLA
NLM
Levine, M. N., Fay, J. W., Jones, N. H., Metzgar, R. S., & Haynes, B. F. (1981). Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. Blood, 58(5), 1047–1049.
Levine, M. N., J. W. Fay, N. H. Jones, R. S. Metzgar, and B. F. Haynes. “Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.” Blood 58, no. 5 (November 1981): 1047–49.
Levine MN, Fay JW, Jones NH, Metzgar RS, Haynes BF. Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. Blood. 1981 Nov;58(5):1047–9.
Levine, M. N., et al. “Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.” Blood, vol. 58, no. 5, Nov. 1981, pp. 1047–49.
Levine MN, Fay JW, Jones NH, Metzgar RS, Haynes BF. Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. Blood. 1981 Nov;58(5):1047–1049.
Published In
Blood
ISSN
0006-4971
Publication Date
November 1981
Volume
58
Issue
5
Start / End Page
1047 / 1049
Location
United States
Related Subject Headings
- Rabbits
- Phenotype
- Macrophages
- Immunology
- Immune Sera
- Humans
- Histocompatibility Antigens Class II
- HLA Antigens
- Granulocytes
- Cytotoxicity, Immunologic