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Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.

Publication ,  Journal Article
Levine, MN; Fay, JW; Jones, NH; Metzgar, RS; Haynes, BF
Published in: Blood
November 1981

Cell surface antigens of the human bone marrow CFU-C have been studied. Human marrow cells were incubated with a variety of monoclonal antisera and complement prior to culture in semisolid media. By using indirect immunofluorescent studies, the percentage of bone marrow cells binding the antibodies was determined. The CFU-C phenotype is HLA+, la+, 4F2+, 3A1-, and DUALL-1-. This study provides information that is useful in the study of myeloid cell ontogeny and necessary for the use of some of these reagents in the treatment of bone marrow cells prior to human bone marrow transplantation in various clinical settings.

Duke Scholars

Published In

Blood

ISSN

0006-4971

Publication Date

November 1981

Volume

58

Issue

5

Start / End Page

1047 / 1049

Location

United States

Related Subject Headings

  • Rabbits
  • Phenotype
  • Macrophages
  • Immunology
  • Immune Sera
  • Humans
  • Histocompatibility Antigens Class II
  • HLA Antigens
  • Granulocytes
  • Cytotoxicity, Immunologic
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Levine, M. N., Fay, J. W., Jones, N. H., Metzgar, R. S., & Haynes, B. F. (1981). Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. Blood, 58(5), 1047–1049.
Levine, M. N., J. W. Fay, N. H. Jones, R. S. Metzgar, and B. F. Haynes. “Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.Blood 58, no. 5 (November 1981): 1047–49.
Levine MN, Fay JW, Jones NH, Metzgar RS, Haynes BF. Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. Blood. 1981 Nov;58(5):1047–9.
Levine, M. N., et al. “Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.Blood, vol. 58, no. 5, Nov. 1981, pp. 1047–49.
Levine MN, Fay JW, Jones NH, Metzgar RS, Haynes BF. Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. Blood. 1981 Nov;58(5):1047–1049.

Published In

Blood

ISSN

0006-4971

Publication Date

November 1981

Volume

58

Issue

5

Start / End Page

1047 / 1049

Location

United States

Related Subject Headings

  • Rabbits
  • Phenotype
  • Macrophages
  • Immunology
  • Immune Sera
  • Humans
  • Histocompatibility Antigens Class II
  • HLA Antigens
  • Granulocytes
  • Cytotoxicity, Immunologic