Synthetic positron emission tomography-computed tomography images for use in perceptual studies.

Journal Article (Journal Article;Review)

To better understand fundamental issues, perception studies of the fusion display would best be performed with a panel of lesions of variable location, size, intensity, and background. There are compelling reasons to use synthetic images that contain artificial lesions for perception research. A consideration of how to obtain this panel of lesions is the nucleus of the present review. This article is a conjoint effort of 3 groups that have joined together to review results from work that they and others have performed. The techniques we review include (1) substitution of lesions into a preexisting image matrix (either using actual prior patient-derived lesions or mathematically modeled artificial lesions), (2) addition of images (either in the attenuation-corrected image space or at an earlier stage before image reconstruction), and (3) simulation of the entire patient image. A judicious combination of the techniques discussed in this review may represent the most efficient pathway of simulating statistically varied but realistic appearing lesions.

Full Text

Duke Authors

Cited Authors

  • D'Alessandro, B; Madsen, M; Samei, E; Li, X; Wooi-Tan, J; Berbaum, KS; Schartz, K; Caldwell, R; Zuckier, LS

Published Date

  • November 2011

Published In

Volume / Issue

  • 41 / 6

Start / End Page

  • 437 - 448

PubMed ID

  • 21978446

Electronic International Standard Serial Number (EISSN)

  • 1558-4623

Digital Object Identifier (DOI)

  • 10.1053/j.semnuclmed.2011.06.007


  • eng

Conference Location

  • United States