Microrheology, stress fluctuations, and active behavior of living cells.
Journal Article (Journal Article)
We report the first measurements of the intrinsic strain fluctuations of living cells using a recently developed tracer correlation technique along with a theoretical framework for interpreting such data in heterogeneous media with nonthermal driving. The fluctuations' spatial and temporal correlations indicate that the cytoskeleton can be treated as a course-grained continuum with power-law rheology, driven by a spatially random stress tensor field. Combined with recent cell rheology results, our data imply that intracellular stress fluctuations have a nearly 1/omega2 power spectrum, as expected for a continuum with a slowly evolving internal prestress.
Full Text
Duke Authors
Cited Authors
- Lau, AW; Hoffman, BD; Davies, A; Crocker, JC; Lubensky, TC
Published Date
- November 2003
Published In
Volume / Issue
- 91 / 19
Start / End Page
- 198101 -
PubMed ID
- 14611619
Electronic International Standard Serial Number (EISSN)
- 1079-7114
International Standard Serial Number (ISSN)
- 0031-9007
Digital Object Identifier (DOI)
- 10.1103/physrevlett.91.198101
Language
- eng