Mechanical ventricular support lowers pulmonary vascular resistance in a patient with congential heart disease.

Journal Article (Journal Article)

Severely elevated pulmonary vascular resistance (PVR) is a relative contraindication to orthotopic heart transplantation. A potential novel strategy to reverse elevated PVR may be implantation of a chronic left ventricular assist device with subsequent left ventricular unloading. We present a patient with elevated PVR secondary to congenital heart disease who was listed for heart-lung transplant. The patient underwent placement of biventricular assist devices and subsequently experienced marked reduction of PVR, ultimately enabling successful heart transplantation.

Full Text

Duke Authors

Cited Authors

  • Petrofski, JA; Hoopes, CW; Bashore, TM; Russell, SD; Milano, CA

Published Date

  • March 2003

Published In

Volume / Issue

  • 75 / 3

Start / End Page

  • 1005 - 1007

PubMed ID

  • 12645735

International Standard Serial Number (ISSN)

  • 0003-4975

Digital Object Identifier (DOI)

  • 10.1016/s0003-4975(02)04372-2


  • eng

Conference Location

  • Netherlands