Mechanical ventricular support lowers pulmonary vascular resistance in a patient with congential heart disease.
Severely elevated pulmonary vascular resistance (PVR) is a relative contraindication to orthotopic heart transplantation. A potential novel strategy to reverse elevated PVR may be implantation of a chronic left ventricular assist device with subsequent left ventricular unloading. We present a patient with elevated PVR secondary to congenital heart disease who was listed for heart-lung transplant. The patient underwent placement of biventricular assist devices and subsequently experienced marked reduction of PVR, ultimately enabling successful heart transplantation.
Petrofski, JA; Hoopes, CW; Bashore, TM; Russell, SD; Milano, CA
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