Sudden death from diffuse leptomeningeal oligodendrogliomatosis.

Journal Article (Journal Article)

In this paper the authors describe the rare disorder of diffuse leptomeningeal oligodendrogliomatosis in a patient with an oligodendroglioma of the cauda equina who died suddenly. Reviewing this uncommon pathological entity is important so that it can be recognized and treated appropriately. This young, otherwise healthy woman with initial symptoms of low-back pain had a mass lesion of the cauda equina. During a workup, profound refractory intracranial hypertension suddenly developed despite aggressive surgical and medical intervention. Autopsy revealed a spinal cord oligodendroglioma with diffuse leptomeningeal oligodendrogliomatosis of the brain and spinal cord. Given the unforeseen outcome in this patient, this entity, although rare, should be considered in patients with similar presentations and addressed early to prevent similar outcomes. A review of the details of this case as well as the literature is presented below.

Full Text

Duke Authors

Cited Authors

  • Reynolds, RM; Boswell, E; Hulette, CM; Cummings, TJ; Haglund, MM; Cumm Ings, TJ

Published Date

  • December 2011

Published In

Volume / Issue

  • 15 / 6

Start / End Page

  • 625 - 629

PubMed ID

  • 21888480

Electronic International Standard Serial Number (EISSN)

  • 1547-5646

Digital Object Identifier (DOI)

  • 10.3171/2011.7.SPINE10728


  • eng

Conference Location

  • United States