Pulmonary hypertension related to left-sided cardiac pathology.


Journal Article

Pulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In patients with left-sided cardiac disease, PH is quite common and associated with increased morbidity and mortality. This article will review the literature as it pertains to the epidemiology, pathogenesis, and diagnosis of PH related to aortic valve disease, mitral valve disease, left ventricular systolic and diastolic dysfunction, and pulmonary veno-occlusive disease. Moreover, therapeutic strategies, which focus on treating the underlying cardiac pathology will be discussed.

Full Text

Duke Authors

Cited Authors

  • Kiefer, TL; Bashore, TM

Published Date

  • 2011

Published In

Volume / Issue

  • 2011 /

Start / End Page

  • 381787 -

PubMed ID

  • 21660234

Pubmed Central ID

  • 21660234

Electronic International Standard Serial Number (EISSN)

  • 2090-1844

Digital Object Identifier (DOI)

  • 10.1155/2011/381787


  • eng

Conference Location

  • Egypt