Comparison of ionic and low-osmolar contrast media during cardiac catheterization.


Journal Article

The use of nonionic contrast agents during cardiac catheterization decreases the incidence of both major and minor cardiovascular complications when compared with ionic contrast. Hemodynamic and electrophysiologic effects are less profound especially in patients who have severe coronary artery disease or left ventricular dysfunction. Sparse data exist comparing ionic and nonionic contrast in patients undergoing percutaneous transluminal coronary angioplasty. No clinical evidence suggests that nonionic contrast agents are less nephrotoxic than ionic contrast though patients with significant baseline renal dysfunction (creatinine > 3.0) might benefit. The incidence of thrombotic events appears to be similar for both types of agents. Finally, the risk reduction of cardiovascular events must be weighed against markedly higher costs.

Full Text

Duke Authors

Cited Authors

  • Davidson, CJ; Bashore, TM

Published Date

  • March 1, 1991

Published In

Volume / Issue

  • 1 / 2

Start / End Page

  • 86 - 91

PubMed ID

  • 21239336

Pubmed Central ID

  • 21239336

International Standard Serial Number (ISSN)

  • 1050-1738

Digital Object Identifier (DOI)

  • 10.1016/1050-1738(91)90016-8


  • eng

Conference Location

  • United States