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Prophylaxis of invasive mycoses in solid organ transplantation.

Publication ,  Journal Article
Alexander, BD
Published in: Curr Opin Infect Dis
December 2002

PURPOSE OF REVIEW: Solid organ transplantation is emerging as a life-saving procedure for increasing numbers of patients and invasive fungal infections are a significant cause of mortality and morbidity for patients undergoing these procedures. This paper will review the latest data pertinent to the development of effective regimens aimed at preventing invasive mycoses in the solid organ transplantation population. RECENT FINDINGS: Risks for developing invasive fungal infections are continuing to evolve, leading to shifts in the epidemiology of invasive mycoses occurring after transplantation. For instance, risks for the development of invasive candidiasis in the immediate postoperative period following orthotopic liver transplantation have decreased dramatically while the incidence of invasive aspergillosis appears to be on the rise. New agents have recently been approved for use in the United States and may have a role in prophylactic strategies aimed at preventing these fungal infections. SUMMARY: An understanding of these issues is crucial to the development of targeted prophylactic regimens for the successful prevention of invasive fungal infections in the solid organ transplant recipient.

Duke Scholars

Published In

Curr Opin Infect Dis

DOI

ISSN

0951-7375

Publication Date

December 2002

Volume

15

Issue

6

Start / End Page

583 / 589

Location

United States

Related Subject Headings

  • Risk Factors
  • Organ Transplantation
  • Mycoses
  • Microbiology
  • Humans
  • Candidiasis
  • Aspergillosis
  • Antifungal Agents
  • 3202 Clinical sciences
  • 1108 Medical Microbiology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Alexander, B. D. (2002). Prophylaxis of invasive mycoses in solid organ transplantation. Curr Opin Infect Dis, 15(6), 583–589. https://doi.org/10.1097/00001432-200212000-00005
Alexander, Barbara D. “Prophylaxis of invasive mycoses in solid organ transplantation.Curr Opin Infect Dis 15, no. 6 (December 2002): 583–89. https://doi.org/10.1097/00001432-200212000-00005.
Alexander BD. Prophylaxis of invasive mycoses in solid organ transplantation. Curr Opin Infect Dis. 2002 Dec;15(6):583–9.
Alexander, Barbara D. “Prophylaxis of invasive mycoses in solid organ transplantation.Curr Opin Infect Dis, vol. 15, no. 6, Dec. 2002, pp. 583–89. Pubmed, doi:10.1097/00001432-200212000-00005.
Alexander BD. Prophylaxis of invasive mycoses in solid organ transplantation. Curr Opin Infect Dis. 2002 Dec;15(6):583–589.

Published In

Curr Opin Infect Dis

DOI

ISSN

0951-7375

Publication Date

December 2002

Volume

15

Issue

6

Start / End Page

583 / 589

Location

United States

Related Subject Headings

  • Risk Factors
  • Organ Transplantation
  • Mycoses
  • Microbiology
  • Humans
  • Candidiasis
  • Aspergillosis
  • Antifungal Agents
  • 3202 Clinical sciences
  • 1108 Medical Microbiology