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Distinguishing between early and late responders to symptoms of acute myocardial infarction.

Publication ,  Journal Article
Burnett, RE; Blumenthal, JA; Mark, DB; Leimberger, JD; Califf, RM
Published in: Am J Cardiol
May 15, 1995

The present study identified factors that distinguish early responders (i.e., requested medical assistance < 60 minutes after the onset of acute myocardial infarction [AMI] symptoms) from late responders (i.e., request made > or = 60 minutes after symptom onset). A questionnaire developed to assess demographic characteristics, contextual factors, antecedents to symptom onset, and behavioral, affective, and cognitive responses was administered in the hospital to 501 patients with documented AMI. Patients who believed that their symptoms were cardiac in nature were more likely to be early responders, whereas patients who attributed their symptoms to indigestion, muscle pain, fatigue, or another cause responded later (p < 0.0009). Early responders believed their symptoms to be more serious (p < 0.0001), felt more comfortable seeking medical assistance (p < 0.0001), were more anxious or upset when they first noticed symptoms (p = 0.0118), and perceived that they had less control of their symptoms (p < 0.0001) than late responders. A stepwise multiple regression analysis further suggested that unmarried patients responded significantly later than married patients, and patients who first experienced their symptoms at work responded significantly later than those who first experienced their symptoms outside of the home but not at work. These results suggest that situational and psychological variables are important determinants of lengthy decision delays in responding to symptoms of AMI.

Duke Scholars

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

May 15, 1995

Volume

75

Issue

15

Start / End Page

1019 / 1022

Location

United States

Related Subject Headings

  • Tissue Plasminogen Activator
  • Time Factors
  • Thrombolytic Therapy
  • Surveys and Questionnaires
  • Regression Analysis
  • Myocardial Infarction
  • Middle Aged
  • Marital Status
  • Male
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Burnett, R. E., Blumenthal, J. A., Mark, D. B., Leimberger, J. D., & Califf, R. M. (1995). Distinguishing between early and late responders to symptoms of acute myocardial infarction. Am J Cardiol, 75(15), 1019–1022. https://doi.org/10.1016/s0002-9149(99)80716-4
Burnett, R. E., J. A. Blumenthal, D. B. Mark, J. D. Leimberger, and R. M. Califf. “Distinguishing between early and late responders to symptoms of acute myocardial infarction.Am J Cardiol 75, no. 15 (May 15, 1995): 1019–22. https://doi.org/10.1016/s0002-9149(99)80716-4.
Burnett RE, Blumenthal JA, Mark DB, Leimberger JD, Califf RM. Distinguishing between early and late responders to symptoms of acute myocardial infarction. Am J Cardiol. 1995 May 15;75(15):1019–22.
Burnett, R. E., et al. “Distinguishing between early and late responders to symptoms of acute myocardial infarction.Am J Cardiol, vol. 75, no. 15, May 1995, pp. 1019–22. Pubmed, doi:10.1016/s0002-9149(99)80716-4.
Burnett RE, Blumenthal JA, Mark DB, Leimberger JD, Califf RM. Distinguishing between early and late responders to symptoms of acute myocardial infarction. Am J Cardiol. 1995 May 15;75(15):1019–1022.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

May 15, 1995

Volume

75

Issue

15

Start / End Page

1019 / 1022

Location

United States

Related Subject Headings

  • Tissue Plasminogen Activator
  • Time Factors
  • Thrombolytic Therapy
  • Surveys and Questionnaires
  • Regression Analysis
  • Myocardial Infarction
  • Middle Aged
  • Marital Status
  • Male
  • Humans