Clinical correlates and prognostic significance of type A behavior and silent myocardial ischemia on the treadmill.

Published

Journal Article

Type A patients with coronary artery disease (CAD) tend to ignore or underreport symptoms, especially during challenging tasks such as the treadmill exercise test. To determine whether type A CAD patients might be more likely than type B patients to have silent ischemia during exercise and consequently a worse prognosis, 403 patients with stable CAD who had significant coronary disease on angiography, a positive Bruce protocol treadmill test and a structured interview to assess type A behavior were studied. Median follow-up time was 6 years. Type A patients were more likely to experience silent ischemia during exercise than were type B patients (35 vs 25%, p = 0.05). Patients with silent ischemia during exercise had a history of fewer anginal episodes/week, and type A patients with silent ischemia were less likely to have had a history of typical angina. However, using the Cox model, there were no significant differences in survival between type A patients and B patients with silent ischemia (4-year survival 86 vs 79%, p = 0.44) and no significant differences in survival between type A patients with silent ischemia and type A patients with symptomatic ischemia (6-year survival 86 vs 80%, p = 0.59). Similar results were obtained for infarction-free survival. Type A patients are more likely than type B patients to have silent ischemia during exercise, but long-term survival is not affected.

Full Text

Duke Authors

Cited Authors

  • Siegel, WC; Mark, DB; Hlatky, MA; Harrell, FE; Pryor, DB; Barefoot, JC; Williams, RB

Published Date

  • December 1, 1989

Published In

Volume / Issue

  • 64 / 19

Start / End Page

  • 1280 - 1283

PubMed ID

  • 2589193

Pubmed Central ID

  • 2589193

International Standard Serial Number (ISSN)

  • 0002-9149

Digital Object Identifier (DOI)

  • 10.1016/0002-9149(89)90568-7

Language

  • eng

Conference Location

  • United States