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Clopidogrel use and bleeding after coronary artery bypass graft surgery.

Publication ,  Journal Article
Kim, JH-J; Newby, LK; Clare, RM; Shaw, LK; Lodge, AJ; Smith, PK; Jolicoeur, EM; Rao, SV; Becker, RC; Mark, DB; Granger, CB
Published in: Am Heart J
November 2008

BACKGROUND: Short-term use of clopidogrel plus aspirin among patients with acute coronary syndrome reduces ischemic events, but concerns about coronary artery bypass graft (CABG) surgery-related bleeding limit its early use. METHODS: Using data from 4,794 consecutive CABG procedures in the Duke Databank for Cardiovascular Disease (January 1999 to December 2003), we developed multivariable models for associations with CABG-related bleeding defined as reoperation for bleeding, red cell transfusion, and a composite of reoperation/transfusion/hematocrit drop>or=15%. We examined clopidogrel use

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Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

November 2008

Volume

156

Issue

5

Start / End Page

886 / 892

Location

United States

Related Subject Headings

  • Ticlopidine
  • Postoperative Hemorrhage
  • Platelet Aggregation Inhibitors
  • Middle Aged
  • Male
  • Humans
  • Female
  • Coronary Artery Bypass
  • Clopidogrel
  • Cardiovascular System & Hematology
 

Citation

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Kim, J.-J., Newby, L. K., Clare, R. M., Shaw, L. K., Lodge, A. J., Smith, P. K., … Granger, C. B. (2008). Clopidogrel use and bleeding after coronary artery bypass graft surgery. Am Heart J, 156(5), 886–892. https://doi.org/10.1016/j.ahj.2008.06.034
Kim, John Hyung-Jun, L Kristin Newby, Robert M. Clare, Linda K. Shaw, Andrew J. Lodge, Peter K. Smith, E Marc Jolicoeur, et al. “Clopidogrel use and bleeding after coronary artery bypass graft surgery.Am Heart J 156, no. 5 (November 2008): 886–92. https://doi.org/10.1016/j.ahj.2008.06.034.
Kim JH-J, Newby LK, Clare RM, Shaw LK, Lodge AJ, Smith PK, et al. Clopidogrel use and bleeding after coronary artery bypass graft surgery. Am Heart J. 2008 Nov;156(5):886–92.
Kim, John Hyung-Jun, et al. “Clopidogrel use and bleeding after coronary artery bypass graft surgery.Am Heart J, vol. 156, no. 5, Nov. 2008, pp. 886–92. Pubmed, doi:10.1016/j.ahj.2008.06.034.
Kim JH-J, Newby LK, Clare RM, Shaw LK, Lodge AJ, Smith PK, Jolicoeur EM, Rao SV, Becker RC, Mark DB, Granger CB. Clopidogrel use and bleeding after coronary artery bypass graft surgery. Am Heart J. 2008 Nov;156(5):886–892.
Journal cover image

Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

November 2008

Volume

156

Issue

5

Start / End Page

886 / 892

Location

United States

Related Subject Headings

  • Ticlopidine
  • Postoperative Hemorrhage
  • Platelet Aggregation Inhibitors
  • Middle Aged
  • Male
  • Humans
  • Female
  • Coronary Artery Bypass
  • Clopidogrel
  • Cardiovascular System & Hematology