Clopidogrel use and bleeding after coronary artery bypass graft surgery.

Journal Article (Journal Article)

BACKGROUND: Short-term use of clopidogrel plus aspirin among patients with acute coronary syndrome reduces ischemic events, but concerns about coronary artery bypass graft (CABG) surgery-related bleeding limit its early use. METHODS: Using data from 4,794 consecutive CABG procedures in the Duke Databank for Cardiovascular Disease (January 1999 to December 2003), we developed multivariable models for associations with CABG-related bleeding defined as reoperation for bleeding, red cell transfusion, and a composite of reoperation/transfusion/hematocrit drop>or=15%. We examined clopidogrel use

Full Text

Duke Authors

Cited Authors

  • Kim, JH-J; Newby, LK; Clare, RM; Shaw, LK; Lodge, AJ; Smith, PK; Jolicoeur, EM; Rao, SV; Becker, RC; Mark, DB; Granger, CB

Published Date

  • November 2008

Published In

Volume / Issue

  • 156 / 5

Start / End Page

  • 886 - 892

PubMed ID

  • 19061702

Electronic International Standard Serial Number (EISSN)

  • 1097-6744

Digital Object Identifier (DOI)

  • 10.1016/j.ahj.2008.06.034


  • eng

Conference Location

  • United States