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Physician-diagnosed depression as a correlate of hospitalizations in patients receiving long-term hemodialysis.

Publication ,  Journal Article
Hedayati, SS; Grambow, SC; Szczech, LA; Stechuchak, KM; Allen, AS; Bosworth, HB
Published in: Am J Kidney Dis
October 2005

BACKGROUND: Hospital admissions consume a large proportion of costs for the end-stage renal disease (ESRD) program in the United States. We investigated whether a physician diagnosis of depression increases the risk for hospitalization or death in patients with ESRD receiving long-term hemodialysis (HD), independent of medical comorbidities. METHODS: Centralized Veterans Affairs (VA) databases were used to identify a population-based prevalence cohort of 1,588 male patients with ESRD receiving long-term HD in VA facilities between September 1, 2000, and September 30, 2000. International Classification of Diseases, Ninth Revision, codes were used to identify comorbidities and depression diagnosis. Negative binomial regression models were used to examine the association between depression diagnosis and number of hospitalizations and cumulative hospital days in a 2-year observation period. Logistic regression models were used to investigate the association between depression diagnosis and hospitalization, death, and death or hospitalization. RESULTS: The prevalence of physician-diagnosed depression was 14.7%. Patients with a depression diagnosis were more likely to be white and have more comorbidities. Depression diagnosis was associated with increased hospital days (rate ratio for adjusted model, 1.31; 95% confidence interval, 1.04 to 1.66) and increased number of hospitalizations (rate ratio for adjusted model, 1.30; 95% confidence interval, 1.11 to 1.52). Depression diagnosis was not statistically associated with death or the composite of death or hospitalization in adjusted models. CONCLUSION: Physician-diagnosed depression was associated significantly with both increased hospitalization rate and length of stay in patients with ESRD receiving outpatient HD in VA facilities, independent of demographics and comorbidities. Prospective studies should be conducted to assess whether treatment of depression will decrease hospitalization in these patients.

Duke Scholars

Published In

Am J Kidney Dis

DOI

EISSN

1523-6838

Publication Date

October 2005

Volume

46

Issue

4

Start / End Page

642 / 649

Location

United States

Related Subject Headings

  • Veterans
  • Urology & Nephrology
  • United States
  • Time Factors
  • Risk
  • Retrospective Studies
  • Renal Dialysis
  • Prevalence
  • Outpatients
  • Mortality
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hedayati, S. S., Grambow, S. C., Szczech, L. A., Stechuchak, K. M., Allen, A. S., & Bosworth, H. B. (2005). Physician-diagnosed depression as a correlate of hospitalizations in patients receiving long-term hemodialysis. Am J Kidney Dis, 46(4), 642–649. https://doi.org/10.1053/j.ajkd.2005.07.002
Hedayati, S Susan, Steven C. Grambow, Lynda A. Szczech, Karen M. Stechuchak, Andrew S. Allen, and Hayden B. Bosworth. “Physician-diagnosed depression as a correlate of hospitalizations in patients receiving long-term hemodialysis.Am J Kidney Dis 46, no. 4 (October 2005): 642–49. https://doi.org/10.1053/j.ajkd.2005.07.002.
Hedayati SS, Grambow SC, Szczech LA, Stechuchak KM, Allen AS, Bosworth HB. Physician-diagnosed depression as a correlate of hospitalizations in patients receiving long-term hemodialysis. Am J Kidney Dis. 2005 Oct;46(4):642–9.
Hedayati, S. Susan, et al. “Physician-diagnosed depression as a correlate of hospitalizations in patients receiving long-term hemodialysis.Am J Kidney Dis, vol. 46, no. 4, Oct. 2005, pp. 642–49. Pubmed, doi:10.1053/j.ajkd.2005.07.002.
Hedayati SS, Grambow SC, Szczech LA, Stechuchak KM, Allen AS, Bosworth HB. Physician-diagnosed depression as a correlate of hospitalizations in patients receiving long-term hemodialysis. Am J Kidney Dis. 2005 Oct;46(4):642–649.
Journal cover image

Published In

Am J Kidney Dis

DOI

EISSN

1523-6838

Publication Date

October 2005

Volume

46

Issue

4

Start / End Page

642 / 649

Location

United States

Related Subject Headings

  • Veterans
  • Urology & Nephrology
  • United States
  • Time Factors
  • Risk
  • Retrospective Studies
  • Renal Dialysis
  • Prevalence
  • Outpatients
  • Mortality