Patient Specific Dosimetry Phantoms Using Multichannel LDDMM of the Whole Body.

Journal Article (Journal Article)

This paper describes an automated procedure for creating detailed patient-specific pediatric dosimetry phantoms from a small set of segmented organs in a child's CT scan. The algorithm involves full body mappings from adult template to pediatric images using multichannel large deformation diffeomorphic metric mapping (MC-LDDMM). The parallel implementation and performance of MC-LDDMM for this application is studied here for a sample of 4 pediatric patients, and from 1 to 24 processors. 93.84% of computation time is parallelized, and the efficiency of parallelization remains high until more than 8 processors are used. The performance of the algorithm was validated on a set of 24 male and 18 female pediatric patients. It was found to be accurate typically to within 1-2 voxels (2-4 mm) and robust across this large and variable data set.

Full Text

Duke Authors

Cited Authors

  • Tward, DJ; Ceritoglu, C; Kolasny, A; Sturgeon, GM; Segars, WP; Miller, MI; Ratnanather, JT

Published Date

  • 2011

Published In

Volume / Issue

  • 2011 /

Start / End Page

  • 481064 -

PubMed ID

  • 21960989

Pubmed Central ID

  • PMC3180076

Electronic International Standard Serial Number (EISSN)

  • 1687-4196

Digital Object Identifier (DOI)

  • 10.1155/2011/481064


  • eng

Conference Location

  • United States