Evaluation of acute renal failure with magnetic resonance imaging using gradient-echo and Gd-DTPA.

Journal Article (Journal Article)

Detection of acute renal failure (ARF) using fast-scan magnetic resonance imaging (MRI) with Gd-DTPA was studied in a dog model. ARF was produced in five dogs by infusion of norepinephrine (0.75 micrograms/kg/min) into the renal arteries for 40 minutes. MRI was performed 1 hour later and compared with baseline (pre-ARF) MRI. There was no significant difference in the ratios of signal intensity-vs.-time curves from 0 to 35 seconds after injection of Gd-DTPA. However, a difference between the outer and inner medulla was significant in the time period of 5 to 20 minutes after Gd-DTPA injection. These later signal intensity differences by fast-scan (gradient-echo) technique may be useful in the evaluation of ARF.

Full Text

Duke Authors

Cited Authors

  • Munechika, H; Sullivan, DC; Hedlund, LW; Beam, CA; Sostman, HD; Herfkens, RJ; Pelc, NJ

Published Date

  • January 1, 1991

Published In

Volume / Issue

  • 26 / 1

Start / End Page

  • 22 - 27

PubMed ID

  • 2022449

International Standard Serial Number (ISSN)

  • 0020-9996

Digital Object Identifier (DOI)

  • 10.1097/00004424-199101000-00005


  • eng

Conference Location

  • United States