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Breast carcinoma: MR imaging before re-excisional biopsy.

Publication ,  Journal Article
Orel, SG; Reynolds, C; Schnall, MD; Solin, LJ; Fraker, DL; Sullivan, DC
Published in: Radiology
November 1997

PURPOSE: To investigate the role of magnetic resonance (MR) imaging in the examination of patients after excisional biopsy of breast carcinoma before re-excision. MATERIALS AND METHODS: Forty-seven patients underwent contrast material-enhanced MR imaging after initial excisional biopsy of breast carcinoma before further surgery. RESULTS: The positive predictive value of MR imaging for predicting residual disease was 82%; the negative predictive value was 61%. Fourteen patients had multifocal (n = 6) or diffuse (n = 8) carcinoma. The extent of tumor was correctly identified with MR imaging alone in nine of the 14 patients, with both mammography and MR imaging in three patients, with mammography alone in one patient, and with no imaging modality in one patient. In four of the 14 patients, management was altered from re-excision to mastectomy (n = 3) or from breast-conservation therapy to mastectomy (n = 1). CONCLUSION: MR imaging has a high positive predictive value for predicting residual tumor after excisional biopsy. The identification of mammographically and clinically unsuspected multifocal or extensive residual tumor may lend support for mastectomy rather than re-excision. However, false-negative findings due to postsurgical changes and false-positive findings due to enhancement of granulation tissue and benign breast tissue remain limitations.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

November 1997

Volume

205

Issue

2

Start / End Page

429 / 436

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Reoperation
  • Predictive Value of Tests
  • Nuclear Medicine & Medical Imaging
  • Neoplasm, Residual
  • Middle Aged
  • Mammography
  • Magnetic Resonance Imaging
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Orel, S. G., Reynolds, C., Schnall, M. D., Solin, L. J., Fraker, D. L., & Sullivan, D. C. (1997). Breast carcinoma: MR imaging before re-excisional biopsy. Radiology, 205(2), 429–436. https://doi.org/10.1148/radiology.205.2.9356624
Orel, S. G., C. Reynolds, M. D. Schnall, L. J. Solin, D. L. Fraker, and D. C. Sullivan. “Breast carcinoma: MR imaging before re-excisional biopsy.Radiology 205, no. 2 (November 1997): 429–36. https://doi.org/10.1148/radiology.205.2.9356624.
Orel SG, Reynolds C, Schnall MD, Solin LJ, Fraker DL, Sullivan DC. Breast carcinoma: MR imaging before re-excisional biopsy. Radiology. 1997 Nov;205(2):429–36.
Orel, S. G., et al. “Breast carcinoma: MR imaging before re-excisional biopsy.Radiology, vol. 205, no. 2, Nov. 1997, pp. 429–36. Pubmed, doi:10.1148/radiology.205.2.9356624.
Orel SG, Reynolds C, Schnall MD, Solin LJ, Fraker DL, Sullivan DC. Breast carcinoma: MR imaging before re-excisional biopsy. Radiology. 1997 Nov;205(2):429–436.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

November 1997

Volume

205

Issue

2

Start / End Page

429 / 436

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Reoperation
  • Predictive Value of Tests
  • Nuclear Medicine & Medical Imaging
  • Neoplasm, Residual
  • Middle Aged
  • Mammography
  • Magnetic Resonance Imaging
  • Humans
  • Female