Effects of ECT on brain structure: a pilot prospective magnetic resonance imaging study.


Journal Article

The authors describe a pilot prospective investigation of the effects of ECT on brain structure using magnetic resonance imaging (MRI). In nine patients with major depression, a course of ECT produced no acute changes in brain structure according to blind raters' assessments of cortical atrophy and global comparison of pre- and post-ECT studies. There were also no significant changes in the ventricle-brain ratios. Pre-ECT brain abnormalities were common in these patients yet were also unaffected by ECT. Future MRI studies of ECT should include more subjects and should address long-term changes and subtle brain abnormalities.

Full Text

Duke Authors

Cited Authors

  • Coffey, CE; Figiel, GS; Djang, WT; Sullivan, DC; Herfkens, RJ; Weiner, RD

Published Date

  • June 1988

Published In

Volume / Issue

  • 145 / 6

Start / End Page

  • 701 - 706

PubMed ID

  • 3369556

Pubmed Central ID

  • 3369556

International Standard Serial Number (ISSN)

  • 0002-953X

Digital Object Identifier (DOI)

  • 10.1176/ajp.145.6.701


  • eng

Conference Location

  • United States