Meeting report: high-throughput technologies for in vivo imaging agents.

Published

Journal Article

Combinatorial chemistry and high-throughput screening have become standard tools for discovering new drug candidates with suitable pharmacological properties. Now, those same technologies are starting to be applied to the problem of discovering novel in vivo imaging agents. Important differences in the biological and pharmacological properties needed for imaging agents, compared to those for a therapeutic agent, require new screening methods that emphasize those characteristics, such as optimized residence time and tissue specificity, that make for a good imaging agent candidate.

Full Text

Duke Authors

Cited Authors

  • Gillies, RJ; Hoffman, JM; Lam, KS; Menkens, AE; Piwnica-Worms, DR; Sullivan, DC; Weissleder, R

Published Date

  • April 2005

Published In

Volume / Issue

  • 4 / 2

Start / End Page

  • 98 - 103

PubMed ID

  • 16105507

Pubmed Central ID

  • 16105507

Electronic International Standard Serial Number (EISSN)

  • 1536-0121

International Standard Serial Number (ISSN)

  • 1535-3508

Digital Object Identifier (DOI)

  • 10.1162/15353500200505115

Language

  • eng