Evolutionary crossroads in developmental biology: sea urchins.

Published

Journal Article (Review)

Embryos of the echinoderms, especially those of sea urchins and sea stars, have been studied as model organisms for over 100 years. The simplicity of their early development, and the ease of experimentally perturbing this development, provides an excellent platform for mechanistic studies of cell specification and morphogenesis. As a result, echinoderms have contributed significantly to our understanding of many developmental mechanisms, including those that govern the structure and design of gene regulatory networks, those that direct cell lineage specification, and those that regulate the dynamic morphogenetic events that shape the early embryo.

Full Text

Duke Authors

Cited Authors

  • McClay, DR

Published Date

  • July 2011

Published In

Volume / Issue

  • 138 / 13

Start / End Page

  • 2639 - 2648

PubMed ID

  • 21652646

Pubmed Central ID

  • 21652646

Electronic International Standard Serial Number (EISSN)

  • 1477-9129

International Standard Serial Number (ISSN)

  • 0950-1991

Digital Object Identifier (DOI)

  • 10.1242/dev.048967

Language

  • eng