Trends in the indications for penetrating keratoplasty, 1980-2001.

Journal Article (Journal Article)

PURPOSE: To study the leading indications and changing trends for penetrating keratoplasty (PK) over the past 3 decades. METHODS: This is a retrospective review of 696 cases of PK. The indications for PKs performed at the Duke University Eye Center during the years 1980-1981, 1990- 1991, and 2000-2001 were tabulated to determine trends over the past 3 decades. The main outcome measures were indications for PK. RESULTS: During this study, 696 PKs were performed. The leading indications for PK and their respective frequencies during 1980-1981, 1990-1991, and 2000-2001 were failed grafts (10.8%, 19.0%, 27.0%, respectively), pseudophakic bullous keratopathy (PBK)/aphakic bullous keratopathy (ABK) (19.4%, 20.6%, 16.7%, respectively), Fuchs dystrophy (15.6%, 13.0%, 23.8%, respectively), keratoconus (13.4%, 8.2%, 11.8%, respectively), and corneal scar (7.0%, 8.9%, 10.7%, respectively). The number of PKs for failed grafts and Fuchs dystrophy increased over time. CONCLUSIONS: In this study, failed graft has gradually become the leading indication for PK, whereas most other studies have reported PBK as the leading indication. Unlike many other studies, Fuchs dystrophy was a common indication for PK.

Full Text

Duke Authors

Cited Authors

  • Kang, PC; Klintworth, GK; Kim, T; Carlson, AN; Adelman, R; Stinnett, S; Afshari, NA

Published Date

  • October 2005

Published In

Volume / Issue

  • 24 / 7

Start / End Page

  • 801 - 803

PubMed ID

  • 16160495

International Standard Serial Number (ISSN)

  • 0277-3740

Digital Object Identifier (DOI)

  • 10.1097/01.ico.0000157407.43699.22


  • eng

Conference Location

  • United States