Hybrid dendritic-linear polyester-ethers for in situ photopolymerization.
Published
Journal Article
Novel first through fourth generation hybrid dendritic-linear copolymers, composed entirely of building blocks known to be biocompatible or degradable to natural metabolites in vivo, are described. Specifically, these copolymers are composed of poly(ethylene glycol), glycerol, and succinic acid and are synthesized using a divergent approach in high yield. A photo-cross-linkable derivative of this copolymer successfully seals 4.1 mm corneal lacerations. The mechanism of tissue repair is likely one of physical entrapment where an interpenetrating network (IPN) is formed between the cross-linked copolymer and the tissue.
Full Text
Duke Authors
Cited Authors
- Carnahan, MA; Middleton, C; Kim, J; Kim, T; Grinstaff, MW
Published Date
- May 15, 2002
Published In
Volume / Issue
- 124 / 19
Start / End Page
- 5291 - 5293
PubMed ID
- 11996569
Pubmed Central ID
- 11996569
International Standard Serial Number (ISSN)
- 0002-7863
Digital Object Identifier (DOI)
- 10.1021/ja025576y
Language
- eng
Conference Location
- United States