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Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior.

Publication ,  Journal Article
Latendresse, SJ; Bates, JE; Goodnight, JA; Lansford, JE; Budde, JP; Goate, A; Dodge, KA; Pettit, GS; Dick, DM
Published in: Child development
November 2011

The present study characterized prototypical patterns of development in self-reported externalizing behavior, between 12 and 22 years of age, within a community sample of 452 genotyped individuals. A Caucasian subset (n = 378) was then examined to determine whether their probabilities of displaying discrete trajectories were differentially associated with CHRM2, a gene implicated in self-regulatory processes across a range of externalizing behaviors, and if affiliating with antisocial peers moderated these associations. Findings indicate that relative to a normative "lower risk" externalizing trajectory, likelihood of membership in two "higher risk" trajectories increased with each additional copy of the minor allelic variant at CHRM2, and that this association was exacerbated among those exposed to higher levels of peer group antisocial behavior.

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Published In

Child development

DOI

EISSN

1467-8624

ISSN

0009-3920

Publication Date

November 2011

Volume

82

Issue

6

Start / End Page

1797 / 1814

Related Subject Headings

  • Young Adult
  • Social Identification
  • Social Facilitation
  • Receptor, Muscarinic M2
  • Polymorphism, Single Nucleotide
  • Peer Group
  • Male
  • Internal-External Control
  • Humans
  • Genotype
 

Citation

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ICMJE
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Latendresse, S. J., Bates, J. E., Goodnight, J. A., Lansford, J. E., Budde, J. P., Goate, A., … Dick, D. M. (2011). Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. Child Development, 82(6), 1797–1814. https://doi.org/10.1111/j.1467-8624.2011.01640.x
Latendresse, Shawn J., John E. Bates, Jackson A. Goodnight, Jennifer E. Lansford, John P. Budde, Alison Goate, Kenneth A. Dodge, Gregory S. Pettit, and Danielle M. Dick. “Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior.Child Development 82, no. 6 (November 2011): 1797–1814. https://doi.org/10.1111/j.1467-8624.2011.01640.x.
Latendresse SJ, Bates JE, Goodnight JA, Lansford JE, Budde JP, Goate A, et al. Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. Child development. 2011 Nov;82(6):1797–814.
Latendresse, Shawn J., et al. “Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior.Child Development, vol. 82, no. 6, Nov. 2011, pp. 1797–814. Epmc, doi:10.1111/j.1467-8624.2011.01640.x.
Latendresse SJ, Bates JE, Goodnight JA, Lansford JE, Budde JP, Goate A, Dodge KA, Pettit GS, Dick DM. Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. Child development. 2011 Nov;82(6):1797–1814.
Journal cover image

Published In

Child development

DOI

EISSN

1467-8624

ISSN

0009-3920

Publication Date

November 2011

Volume

82

Issue

6

Start / End Page

1797 / 1814

Related Subject Headings

  • Young Adult
  • Social Identification
  • Social Facilitation
  • Receptor, Muscarinic M2
  • Polymorphism, Single Nucleotide
  • Peer Group
  • Male
  • Internal-External Control
  • Humans
  • Genotype