Imaginary magnetic tweezers for massively parallel surface adhesion spectroscopy.

Journal Article (Journal Article)

A massively parallel magnetic tweezer system has been constructed that utilizes the self-repulsion of colloidal beads from a planar interface via a magnetic dipole image force. Self-repulsion enables the application of a uniform magnetic force to thousands of beads simultaneously, which permits the measurement of unbinding histograms at the lowest loading rates ever tested. The adhesion of 9.8 μm polystyrene beads to a fluorocarbon, PEG, and UV-irradiated PEG surfaces were measured between 10(-3)-10(0) pN/s force loading rates, revealing the presence of both kinetic and quasi-equilibrium unbinding regimes.

Full Text

Duke Authors

Cited Authors

  • Yang, Y; Erb, RM; Wiley, BJ; Zauscher, S; Yellen, BB

Published Date

  • April 2011

Published In

Volume / Issue

  • 11 / 4

Start / End Page

  • 1681 - 1684

PubMed ID

  • 21417363

Electronic International Standard Serial Number (EISSN)

  • 1530-6992

International Standard Serial Number (ISSN)

  • 1530-6984

Digital Object Identifier (DOI)

  • 10.1021/nl200189w


  • eng