Neuropsychological assessment, neuroimaging, and neuropsychiatric evaluation in pediatric and adult patients with sickle cell disease (SCD).

Journal Article (Journal Article)

Traditionally, neuropsychological deficits due to Sickle Cell Disease (SCD) have been understudied in adults. We have begun to suspect, however, that symptomatic and asymptomatic Cerebrovascular Events (CVE) may account for an alarming number of deficits in this population. In the current brief review, we critically evaluated the pediatric and adult literatures on the neurocognitive effects of SCD. We highlighted the studies that have been published on this topic and posit that early detection of CVE via neurocognitive testing, neuropsychiatric evaluations, and neuroimaging may significantly reduce adult cognitive and functional morbidities.

Full Text

Duke Authors

Cited Authors

  • Edwards, CL; Raynor, RD; Feliu, M; McDougald, C; Johnson, S; Schmechel, D; Wood, M; Bennett, GG; Saurona, P; Bonner, M; Wellington, C; DeCastro, LM; Whitworth, E; Abrams, M; Logue, P; Edwards, L; Martinez, S; Whitfield, KE

Published Date

  • December 2007

Published In

Volume / Issue

  • 3 / 6

Start / End Page

  • 705 - 709

PubMed ID

  • 19300604

Pubmed Central ID

  • PMC2656311

International Standard Serial Number (ISSN)

  • 1176-6328

Digital Object Identifier (DOI)

  • 10.2147/ndt.s518


  • eng

Conference Location

  • New Zealand