Dynamic correction of artifacts due to susceptibility effects and time-varying eddy currents in diffusion tensor imaging.

Journal Article (Journal Article)

In diffusion tensor imaging (DTI), spatial and temporal variations of the static magnetic field (B(0)) caused by susceptibility effects and time-varying eddy currents result in severe distortions, blurring, and misregistration artifacts, which in turn lead to errors in DTI metrics and in fiber tractography. Various correction methods have been proposed, but typically assume that the eddy current-induced magnetic field can be modeled as a constant or a single exponential decay within the DTI readout window. Here, we show that its temporal dependence is more complex because of the interaction of multiple eddy currents with different time constants, but that it remains very consistent over time. As such, we propose a novel dynamic B(0) mapping and off-resonance correction method that measures the exact spatial, temporal, and diffusion-weighting direction dependence of the susceptibility- and eddy current-induced magnetic fields to effectively and efficiently correct for artifacts caused by both susceptibility effects and time-varying eddy currents, thereby resulting in a high spatial fidelity and accuracy.

Full Text

Duke Authors

Cited Authors

  • Truong, T-K; Chen, N-K; Song, AW

Published Date

  • August 15, 2011

Published In

Volume / Issue

  • 57 / 4

Start / End Page

  • 1343 - 1347

PubMed ID

  • 21689763

Pubmed Central ID

  • PMC3138839

Electronic International Standard Serial Number (EISSN)

  • 1095-9572

Digital Object Identifier (DOI)

  • 10.1016/j.neuroimage.2011.06.008


  • eng

Conference Location

  • United States