Blipped multi gradient-echo slice excitation profile imaging (bmGESEPI) for fast T2 * measurements with macroscopic B0 inhomogeneity compensation.

Journal Article (Journal Article)

With the rapid development of human MRI at field strengths > or = 7 T, knowledge of T(2) (*) relaxation times at such field strengths is needed to optimize acquisition parameters and understand relaxation mechanisms in many applications. However, standard T(2) (*) measurements (e.g., using conventional multiecho gradient-echo (GE) sequences) are affected by macroscopic static magnetic field (B(0)) inhomogeneities, which are particularly severe at high field strength. The multi-GE slice excitation profile imaging (mGESEPI) method was developed for T(2) (*) measurements in the presence of macroscopic B(0) inhomogeneity, but it requires excessive acquisition times at field strengths > or = 7 T. In this paper a more efficient technique, named blipped mGESEPI (bmGESEPI), is proposed. To demonstrate its advantages, T(2) (*) maps were acquired using a conventional multiecho GE method, the mGESEPI method, and the bmGESEPI method in postmortem and in vivo human brains at 8 T.

Full Text

Duke Authors

Cited Authors

  • Truong, T-K; Chakeres, DW; Scharre, DW; Beversdorf, DQ; Schmalbrock, P

Published Date

  • June 2006

Published In

Volume / Issue

  • 55 / 6

Start / End Page

  • 1390 - 1395

PubMed ID

  • 16685734

International Standard Serial Number (ISSN)

  • 0740-3194

Digital Object Identifier (DOI)

  • 10.1002/mrm.20916


  • eng

Conference Location

  • United States