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Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy.

Publication ,  Journal Article
Hoffman, DW; Venters, RA; Shedd, SF; Spicer, LD
Published in: Magn Reson Med
March 1990

Analysis of biological fluids by proton magnetic resonance spectroscopy is often complicated by dynamic range problems created from the large water resonance. Gel filtration chromatography is found to be a simple and nondestructive method for exchanging D2O for H2O and for removing low molecular weight molecules from both plasma and urine, significantly improving subsequent one- and two-dimensional MRS spectra.

Duke Scholars

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

March 1990

Volume

13

Issue

3

Start / End Page

507 / 513

Location

United States

Related Subject Headings

  • Urine
  • Protons
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Lipids
  • Humans
  • Chromatography, Gel
  • Body Water
  • 4003 Biomedical engineering
  • 0903 Biomedical Engineering
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hoffman, D. W., Venters, R. A., Shedd, S. F., & Spicer, L. D. (1990). Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy. Magn Reson Med, 13(3), 507–513. https://doi.org/10.1002/mrm.1910130319
Hoffman, D. W., R. A. Venters, S. F. Shedd, and L. D. Spicer. “Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy.Magn Reson Med 13, no. 3 (March 1990): 507–13. https://doi.org/10.1002/mrm.1910130319.
Hoffman DW, Venters RA, Shedd SF, Spicer LD. Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy. Magn Reson Med. 1990 Mar;13(3):507–13.
Hoffman, D. W., et al. “Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy.Magn Reson Med, vol. 13, no. 3, Mar. 1990, pp. 507–13. Pubmed, doi:10.1002/mrm.1910130319.
Hoffman DW, Venters RA, Shedd SF, Spicer LD. Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy. Magn Reson Med. 1990 Mar;13(3):507–513.
Journal cover image

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

March 1990

Volume

13

Issue

3

Start / End Page

507 / 513

Location

United States

Related Subject Headings

  • Urine
  • Protons
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Lipids
  • Humans
  • Chromatography, Gel
  • Body Water
  • 4003 Biomedical engineering
  • 0903 Biomedical Engineering