Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy.
Published
Journal Article
Analysis of biological fluids by proton magnetic resonance spectroscopy is often complicated by dynamic range problems created from the large water resonance. Gel filtration chromatography is found to be a simple and nondestructive method for exchanging D2O for H2O and for removing low molecular weight molecules from both plasma and urine, significantly improving subsequent one- and two-dimensional MRS spectra.
Full Text
Duke Authors
Cited Authors
- Hoffman, DW; Venters, RA; Shedd, SF; Spicer, LD
Published Date
- March 1, 1990
Published In
Volume / Issue
- 13 / 3
Start / End Page
- 507 - 513
PubMed ID
- 2157933
Pubmed Central ID
- 2157933
International Standard Serial Number (ISSN)
- 0740-3194
Digital Object Identifier (DOI)
- 10.1002/mrm.1910130319
Language
- eng
Conference Location
- United States