Synthesis of 11C-labeled chlorpromazine directly from [11C]carbon dioxide.
Publication
, Journal Article
Ram, S; Spicer, LD
Published in: Int J Rad Appl Instrum A
1989
Radiolabeled chlorpromazine was prepared by carboxylation of the N-trimethylsilyl derivative of norchlorpromazine with [11C]carbon dioxide, followed by in situ lithium aluminum hydride reduction. Radiochemical yields of 22-24% and radiochemical purities in the range of 93-98% were achieved.
Duke Scholars
Published In
Int J Rad Appl Instrum A
DOI
ISSN
0883-2889
Publication Date
1989
Volume
40
Issue
5
Start / End Page
413 / 416
Location
England
Related Subject Headings
- Isotope Labeling
- Humans
- Chlorpromazine
- Carbon Radioisotopes
- Carbon Dioxide
Citation
APA
Chicago
ICMJE
MLA
NLM
Ram, S., & Spicer, L. D. (1989). Synthesis of 11C-labeled chlorpromazine directly from [11C]carbon dioxide. Int J Rad Appl Instrum A, 40(5), 413–416. https://doi.org/10.1016/0883-2889(89)90207-4
Ram, S., and L. D. Spicer. “Synthesis of 11C-labeled chlorpromazine directly from [11C]carbon dioxide.” Int J Rad Appl Instrum A 40, no. 5 (1989): 413–16. https://doi.org/10.1016/0883-2889(89)90207-4.
Ram S, Spicer LD. Synthesis of 11C-labeled chlorpromazine directly from [11C]carbon dioxide. Int J Rad Appl Instrum A. 1989;40(5):413–6.
Ram, S., and L. D. Spicer. “Synthesis of 11C-labeled chlorpromazine directly from [11C]carbon dioxide.” Int J Rad Appl Instrum A, vol. 40, no. 5, 1989, pp. 413–16. Pubmed, doi:10.1016/0883-2889(89)90207-4.
Ram S, Spicer LD. Synthesis of 11C-labeled chlorpromazine directly from [11C]carbon dioxide. Int J Rad Appl Instrum A. 1989;40(5):413–416.
Published In
Int J Rad Appl Instrum A
DOI
ISSN
0883-2889
Publication Date
1989
Volume
40
Issue
5
Start / End Page
413 / 416
Location
England
Related Subject Headings
- Isotope Labeling
- Humans
- Chlorpromazine
- Carbon Radioisotopes
- Carbon Dioxide