Calcineurin localizes to the hyphal septum in Aspergillus fumigatus: implications for septum formation and conidiophore development.


Journal Article

A functional calcineurin A fusion to enhanced green fluorescent protein (EGFP), CnaA-EGFP, was expressed in the Aspergillus fumigatus DeltacnaA mutant. CnaA-EGFP localized in actively growing hyphal tips, at the septa, and at junctions between the vesicle and phialides in an actin-dependent manner. This is the first study to implicate calcineurin in septum formation and conidiophore development of a filamentous fungus.

Full Text

Duke Authors

Cited Authors

  • Juvvadi, PR; Fortwendel, JR; Pinchai, N; Perfect, BZ; Heitman, J; Steinbach, WJ

Published Date

  • September 2008

Published In

Volume / Issue

  • 7 / 9

Start / End Page

  • 1606 - 1610

PubMed ID

  • 18606829

Pubmed Central ID

  • 18606829

Electronic International Standard Serial Number (EISSN)

  • 1535-9786

Digital Object Identifier (DOI)

  • 10.1128/EC.00200-08


  • eng

Conference Location

  • United States