The effect of rhodopsin phosphorylation on the light-dependent activation of phosphodiesterase from bovine rod outer segments.
Journal Article (Journal Article)
ATP quenches light-dependent phosphodiesterase (PDE) activation in rod outer segments presumably due to rhodopsin phosphorylation. Here we compared the efficiency of phosphorylated and non-phosphorylated rhodopsins as PDE activators in a reconstituted cell-free system. It is shown that the ability of phosphorylated membranes to activate this enzyme is suppressed compared with non-phosphorylated ones.
Full Text
Duke Authors
Cited Authors
- Arshavsky, VY; Dizhoor, AM; Shestakova, IK; Philippov, P
Published Date
- February 25, 1985
Published In
Volume / Issue
- 181 / 2
Start / End Page
- 264 - 266
PubMed ID
- 2982661
International Standard Serial Number (ISSN)
- 0014-5793
Digital Object Identifier (DOI)
- 10.1016/0014-5793(85)80272-6
Language
- eng
Conference Location
- England