The effect of rhodopsin phosphorylation on the light-dependent activation of phosphodiesterase from bovine rod outer segments.

Journal Article (Journal Article)

ATP quenches light-dependent phosphodiesterase (PDE) activation in rod outer segments presumably due to rhodopsin phosphorylation. Here we compared the efficiency of phosphorylated and non-phosphorylated rhodopsins as PDE activators in a reconstituted cell-free system. It is shown that the ability of phosphorylated membranes to activate this enzyme is suppressed compared with non-phosphorylated ones.

Full Text

Duke Authors

Cited Authors

  • Arshavsky, VY; Dizhoor, AM; Shestakova, IK; Philippov, P

Published Date

  • February 25, 1985

Published In

Volume / Issue

  • 181 / 2

Start / End Page

  • 264 - 266

PubMed ID

  • 2982661

International Standard Serial Number (ISSN)

  • 0014-5793

Digital Object Identifier (DOI)

  • 10.1016/0014-5793(85)80272-6


  • eng

Conference Location

  • England