Myosin III illuminates the mechanism of arrestin translocation.

Journal Article (Journal Article;Review)

Recent studies have revealed that light adaptation of both vertebrate and invertebrate photoreceptors is accompanied by massive translocations of major signaling proteins in and out of the cellular compartments where visual signal transduction takes place. In this issue of Neuron, Lee and Montell report a breakthrough in understanding the mechanism of arrestin translocation in Drosophila. They show that arrestin is carried into the light-sensitive microvilli by phosphoinositide-enriched vesicles driven by a myosin motor.

Full Text

Duke Authors

Cited Authors

  • Strissel, KJ; Arshavsky, VY

Published Date

  • July 8, 2004

Published In

Volume / Issue

  • 43 / 1

Start / End Page

  • 2 - 4

PubMed ID

  • 15233912

International Standard Serial Number (ISSN)

  • 0896-6273

Digital Object Identifier (DOI)

  • 10.1016/j.neuron.2004.06.026


  • eng

Conference Location

  • United States