The metabolic evaluation of patients with recurrent nephrolithiasis: a review of comprehensive and simplified approaches.


Journal Article (Review)

The advent of percutaneous nephrostolithotomy and extracorporeal shock wave lithotripsy has definitely altered the way in which symptomatic renal calculi are approached. However, these new techniques should not affect the need for appropriate diagnostic evaluation and institution of medical treatment for the prevention of recurrent nephrolithiasis. A diagnostic evaluation should identify underlying physiological and environmental defects responsible for stone formation, as well as identify specific medical disorders that cause recurrent stone formation. With this information one then can construct an appropriate treatment program that will prevent the occurrence of additional calculi. Comprehensive metabolic protocols have evolved from tedious inpatient procedures to more convenient outpatient tests that can be performed in approximately 2 weeks. In addition, the advent of automated urinalysis packages has allowed many physicians access to reliable, sophisticated technology. Further dissemination of these simplified metabolic protocols will enable more accurate diagnosis of recurrent stone disease and, hopefully, permit the institution of appropriate medical therapy by a wider group of treating physicians.

Full Text

Duke Authors

Cited Authors

  • Preminger, GM

Published Date

  • March 1989

Published In

Volume / Issue

  • 141 / 3 Pt 2

Start / End Page

  • 760 - 763

PubMed ID

  • 2645436

Pubmed Central ID

  • 2645436

International Standard Serial Number (ISSN)

  • 0022-5347

Digital Object Identifier (DOI)

  • 10.1016/s0022-5347(17)41004-4


  • eng

Conference Location

  • United States