Metal nanoshells.

Published

Journal Article (Review)

Metal nanoshells are a new class of nanoparticles with highly tunable optical properties. Metal nanoshells consist of a dielectric core nanoparticle such as silica surrounded by an ultrathin metal shell, often composed of gold for biomedical applications. Depending on the size and composition of each layer of the nanoshell, particles can be designed to either absorb or scatter light over much of the visible and infrared regions of the electromagnetic spectrum, including the near infrared region where penetration of light through tissue is maximal. These particles are also effective substrates for surface-enhanced Raman scattering (SERS) and are easily conjugated to antibodies and other biomolecules. One can envision a myriad of potential applications of such tunable particles. Several potential biomedical applications are under development, including immunoassays, modulated drug delivery, photothermal cancer therapy, and imaging contrast agents.

Full Text

Duke Authors

Cited Authors

  • Hirsch, LR; Gobin, AM; Lowery, AR; Tam, F; Drezek, RA; Halas, NJ; West, JL

Published Date

  • January 2006

Published In

Volume / Issue

  • 34 / 1

Start / End Page

  • 15 - 22

PubMed ID

  • 16528617

Pubmed Central ID

  • 16528617

Electronic International Standard Serial Number (EISSN)

  • 1573-9686

International Standard Serial Number (ISSN)

  • 0090-6964

Digital Object Identifier (DOI)

  • 10.1007/s10439-005-9001-8

Language

  • eng