Laser scanning lithography for surface micropatterning on hydrogels


Journal Article

A versatile confocal-based laser scanning lithographic method for controlled, high-fidelity two-dimensional (2D) and three-dimensional (3D) surface patterning of poly(ethylene glycol)-diacrylate (PEGDA) hydrogels was presented. The surface properties of deformable PEGDA hydrogels were modified using laser scanning lithography (LSL), with pattern feature sizes down to at least 5 μm. Complex 2D concentration gradients of patterned peptides were generated through user alteration of irradiation exposure levels across regions of interest (ROI). 3D surface structures with heights under ∼5 were also created with high fidelity by incorporating PEGDA macromers into the precursor solution.

Full Text

Duke Authors

Cited Authors

  • Hahn, MS; Miller, JS; West, JL

Published Date

  • December 16, 2005

Published In

Volume / Issue

  • 17 / 24

Start / End Page

  • 2939 - 2942

International Standard Serial Number (ISSN)

  • 0935-9648

Digital Object Identifier (DOI)

  • 10.1002/adma.200500184

Citation Source

  • Scopus